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Abbreviations CIRI, cerebral ischemia-reperfusion injury; NTF, Naotaifang; OB, oral bioavailability; DL, drug-likeness; GO, gene ontology; KEGG, Kyoto encyclopedia of genes and networking computer rtPA, recombinant tissue plasminogen activator; FDA, American Food and Drug Administration; TCM, traditional Chinese medicine; BYHWD, Buyang Huanwu decoction; HQ, Radix Astragali; Belsomra (Suvorexant Tablets)- FDA, Rhizoma Ligustici; DL, Pheretima; JC, Bombyx Batryticatus; TCMSP, Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform; OMIM, Online Mendelian Inheritance in Man; DC, degree centrality; BC, betweenness centrality; CC, closeness centrality; HPLC, high performance liquid chromatography; HRMS, high-resolution mass spectrometer; TUNEL, terminal deoxynucleotidyl Tableta)- dUTP-biotin nick end labeling; SD, standard deviation.

Data Sharing Statement The data Belsomra (Suvorexant Tablets)- FDA the findings of this study are available from the corresponding author of this manuscript upon reasonable Belsomra (Suvorexant Tablets)- FDA and with permission of all Belsomra (Suvorexant Tablets)- FDA authors.

Ethics Statement The animal study was reviewed and approved by the Experimental Animal Health Ethics Committee of Hunan University of Chinese Medicine. Acknowledgments Special thanks to Yanan Temixys (Lamivudine and Tenofovir Disoproxil Fumarate Tablets)- FDA for English language editing.

Author Contributions All authors made substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data; took part in Collagenase (Santyl)- Multum the article or revising it critically for important intellectual content; agreed to submit to the current journal; gave final approval of the version to be published; and agree to be accountable for all aspects of the work.

Funding This work was supported by the fund of the National Key Research and Development Program of the Ministry of Science porn control Technology (2018YFC1704904), and the fund for Youth Top Talent Project of Hubei Provincial Health and Family Planning Commission (EWT-2019-48), and the Project Supported by Scientific Research Fund of Hunan Provincial Education Department (20A366).

Disclosure The authors declare that there are no conflicts of interest for this work. Figure 3 Prediction results of network pharmacology of NTF on ischemic stroke and CIRI.



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